Thalidomide-NH-C4-NH-Boc

Modify Date: 2024-01-15 10:24:18

Thalidomide-NH-C4-NH-Boc Structure
Thalidomide-NH-C4-NH-Boc structure
Common Name Thalidomide-NH-C4-NH-Boc
CAS Number 2093388-52-2 Molecular Weight 444.48
Density N/A Boiling Point N/A
Molecular Formula C22H28N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-C4-NH-Boc


Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

 Names

Name Thalidomide-NH-C4-NH-Boc

 Thalidomide-NH-C4-NH-Boc Biological Activity

Description Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Related Catalog
Target

Cereblon

References

[1]. Jiang F, et al.Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem. 2020 Jan 1;28(1):115181.

 Chemical & Physical Properties

Molecular Formula C22H28N4O6
Molecular Weight 444.48

 Safety Information

Hazard Codes Xi
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