58884-35-8

58884-35-8 structure
58884-35-8 structure
  • Name: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
  • Chemical Name: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
  • CAS Number: 58884-35-8
  • Molecular Formula: C9H8N4O
  • Molecular Weight: 188.19
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:12:19
  • Modify Date: 2024-01-14 07:03:06
  • 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
Description 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C9H8N4O
Molecular Weight 188.19
Hazard Codes Xi