58884-35-8

58884-35-8 structure

58884-35-8 structure

Name: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
Chemical Name: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
CAS Number: 58884-35-8
Molecular Formula: C₉H₈N₄O
Molecular Weight: 188.19
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:12:19
Modify Date: 2024-01-14 07:03:06
4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol

Description	4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₉H₈N₄O
Molecular Weight	188.19

Hazard Codes	Xi