4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol

Modify Date: 2024-01-14 07:03:06

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol Structure
4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol structure
Common Name 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
CAS Number 58884-35-8 Molecular Weight 188.19
Density N/A Boiling Point N/A
Molecular Formula C9H8N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol


4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol

 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol Biological Activity

Description 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C9H8N4O
Molecular Weight 188.19

 Safety Information

Hazard Codes Xi