2054345-69-4

2054345-69-4 structure
2054345-69-4 structure
  • Name: Azide-PEG3-L-alanine-Fmoc
  • Chemical Name: Azide-PEG3-L-alanine-Fmoc
  • CAS Number: 2054345-69-4
  • Molecular Formula: C24H28N4O7
  • Molecular Weight: 484.50
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 07:18:42
  • Modify Date: 2024-01-23 12:38:42
  • Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azide-PEG3-L-alanine-Fmoc
Description Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C24H28N4O7
Molecular Weight 484.50