Azide-PEG3-L-alanine-Fmoc

Modify Date: 2025-08-28 06:51:00

Azide-PEG3-L-alanine-Fmoc Structure
Azide-PEG3-L-alanine-Fmoc structure
Common Name Azide-PEG3-L-alanine-Fmoc
CAS Number 2054345-69-4 Molecular Weight 484.50
Density N/A Boiling Point N/A
Molecular Formula C24H28N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azide-PEG3-L-alanine-Fmoc


Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azide-PEG3-L-alanine-Fmoc

 Azide-PEG3-L-alanine-Fmoc Biological Activity

Description Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H28N4O7
Molecular Weight 484.50
InChIKey YTHKPQSMRZQREU-JOCHJYFZSA-N
SMILES [N-]=[N+]=NCCOCCOCCOCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
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