1426174-41-5

1426174-41-5 structure

Name: Ezetimibe phenoxy glucuronide-D4
Chemical Name: Ezetimibe phenoxy glucuronide-D4
CAS Number: 1426174-41-5
Molecular Formula: C₃₀H₂₅D₄F₂NO₉
Molecular Weight: 589.57
Catalog: Research Areas Metabolic Disease
Create Date: 2020-06-01 14:43:29
Modify Date: 2025-08-26 13:58:18
Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].

Name	Ezetimibe phenoxy glucuronide-D4

Description	Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide[1].
References	[1]. Stolk MF, et al. Severe hepatic side effects of ezetimibe. Clin Gastroenterol Hepatol. 2006 Jul;4(7):908-11. [2]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.

Molecular Formula	C₃₀H₂₅D₄F₂NO₉
Molecular Weight	589.57