Ezetimibe phenoxy glucuronide-D4

Modify Date: 2024-01-03 19:26:08

Ezetimibe phenoxy glucuronide-D4 structure	Common Name	Ezetimibe phenoxy glucuronide-D4
	CAS Number	1426174-41-5	Molecular Weight	589.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₅D₄F₂NO₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ezetimibe phenoxy glucuronide-D4

Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].

Name	Ezetimibe phenoxy glucuronide-D4

Description	Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide[1].
References	[1]. Stolk MF, et al. Severe hepatic side effects of ezetimibe. Clin Gastroenterol Hepatol. 2006 Jul;4(7):908-11. [2]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.

Molecular Formula	C₃₀H₂₅D₄F₂NO₉
Molecular Weight	589.57

Ezetimibe phenoxy glucuronide-D4

Use of Ezetimibe phenoxy glucuronide-D4

Names

Ezetimibe phenoxy glucuronide-D4 Biological Activity

Chemical & Physical Properties