2253733-09-2
2253733-09-2 structure
- Name: GSK9311 hydrochloride
- Chemical Name: GSK9311 hydrochloride
- CAS Number: 2253733-09-2
- Molecular Formula: C24H32ClN5O3
- Molecular Weight: 474.00
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2020-06-01 18:41:43
- Modify Date: 2025-08-27 16:26:57
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GSK9311 hydrochloride, a less active analogue of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain with pIC50 values of 6.0 and 4.3 for BRPF1 and BRPF2, respectively[1].
| Name | GSK9311 hydrochloride |
|---|
| Description | GSK9311 hydrochloride, a less active analogue of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain with pIC50 values of 6.0 and 4.3 for BRPF1 and BRPF2, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
BRPF1:6.0 (pIC50) BRPF2:4.3 (pIC50) |
| In Vitro | GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain, and demonstrates properties suitable for cellular and in vivo studies. GSK6853 is a less active analogue of GSK6853 in which the 5-amide is alkylated[1]. |
| References |
| Molecular Formula | C24H32ClN5O3 |
|---|---|
| Molecular Weight | 474.00 |