2376450-73-4

2376450-73-4 structure

2376450-73-4 structure

Name: m-PEG24-alcohol
Chemical Name: m-PEG24-alcohol
CAS Number: 2376450-73-4
Molecular Formula: C₄₉H₁₀₀O₂₅
Molecular Weight: 1089.30
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:29:53
Modify Date: 2024-01-12 21:42:45
m-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG24-alcohol
Synonyms	MFCD27977524

Description	m-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₉H₁₀₀O₂₅
Molecular Weight	1089.30