2226726-55-0

2226726-55-0 structure
2226726-55-0 structure
  • Name: Amino-PEG24-alcohol
  • Chemical Name: Amino-PEG24-alcohol
  • CAS Number: 2226726-55-0
  • Molecular Formula: C48H99NO24
  • Molecular Weight: 1074.29
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:42:15
  • Modify Date: 2024-01-20 18:45:33
  • Amino-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Amino-PEG24-alcohol
Synonyms MFCD21363266
Description Amino-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C48H99NO24
Molecular Weight 1074.29