Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
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Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang
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2408741-87-5

2408741-87-5 structure

2408741-87-5 structure

Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
Chemical Name: Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
CAS Number: 2408741-87-5
Molecular Formula: C₇₈H₁₃₄F₄N₄O₃₅
Molecular Weight: 1763.90
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 15:51:06
Modify Date: 2024-01-08 08:28:22
Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
Synonyms	MFCD28505507

Description	Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₇₈H₁₃₄F₄N₄O₃₅
Molecular Weight	1763.90

Hazard Codes	Xi

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