Mal-PEG4-Glu(TFP ester)-NH-m-PEG24

Modify Date: 2024-01-08 08:28:22

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 structure	Common Name	Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
	CAS Number	2408741-87-5	Molecular Weight	1763.90
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₈H₁₃₄F₄N₄O₃₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mal-PEG4-Glu(TFP ester)-NH-m-PEG24

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG4-Glu(TFP ester)-NH-m-PEG24
Synonym	More Synonyms

Description	Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₇₈H₁₃₄F₄N₄O₃₅
Molecular Weight	1763.90

Hazard Codes	Xi

MFCD28505507