1417700-13-0
1417700-13-0 structure
- Name: ML188
- Chemical Name: ML188
- CAS Number: 1417700-13-0
- Molecular Formula: C26H31N3O3
- Molecular Weight: 433.54
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2020-06-01 12:11:30
- Modify Date: 2024-08-13 22:13:45
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ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity[1].
| Name | ML188 |
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| Description | ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity[1]. |
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| Related Catalog | |
| In Vitro | ML188 (0-30 μM; 48 hours) effectively inhibit SARS-CoV replication in cell culture[1]. Probe ML188 is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action. ML188 yields an antiviral EC50 value ranging from 12.9 to 13.4 μM in mock-infected and SARS-CoV infected cells[1]. Cell Viability Assay[1] Cell Line: Vero E6 cells (mock-infected or infected with SARS-CoV) Concentration: 3, 4, 5, 8,10, 15, 20, 30 μM Incubation Time: 48 hour Result: Against mock-infected and SARS-CoV infected cells. |
| References |
| Molecular Formula | C26H31N3O3 |
|---|---|
| Molecular Weight | 433.54 |
| Hazard Codes | Xi |
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