2112737-71-8

2112737-71-8 structure
2112737-71-8 structure
  • Name: N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
  • Chemical Name: N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
  • CAS Number: 2112737-71-8
  • Molecular Formula: C24H44N2O9
  • Molecular Weight: 504.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-03 14:01:43
  • Modify Date: 2024-01-04 20:10:10
  • N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
Synonyms MFCD30828701
Description N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C24H44N2O9
Molecular Weight 504.61
Hazard Codes Xi