N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)

Modify Date: 2024-01-04 20:10:10

N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) Structure
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) structure
Common Name N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
CAS Number 2112737-71-8 Molecular Weight 504.61
Density N/A Boiling Point N/A
Molecular Formula C24H44N2O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)


N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
Synonym More Synonyms

 N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) Biological Activity

Description N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H44N2O9
Molecular Weight 504.61

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30828701