2183440-74-4

2183440-74-4 structure

2183440-74-4 structure

Name: N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
Chemical Name: N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS Number: 2183440-74-4
Molecular Formula: C₂₉H₅₅N₅O₁₃
Molecular Weight: 681.77
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:28:05
Modify Date: 2024-01-09 18:00:00
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

Description	N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₅₅N₅O₁₃
Molecular Weight	681.77

Hazard Codes	Xi