N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

Modify Date: 2024-01-09 18:00:00

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid structure	Common Name	N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
	CAS Number	2183440-74-4	Molecular Weight	681.77
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₅₅N₅O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

Description	N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₅₅N₅O₁₃
Molecular Weight	681.77

Hazard Codes	Xi