2321366-46-3
2321366-46-3 structure
- Name: Nω-Propyl-L-arginine hydrochloride
- Chemical Name: Nω-Propyl-L-arginine hydrochloride
- CAS Number: 2321366-46-3
- Molecular Formula: C9H21ClN4O2
- Molecular Weight: 252.74
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2020-06-01 10:01:11
- Modify Date: 2023-01-30 19:54:24
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Nω-Propyl-L-arginine hydrochloride (N-omega-Propyl-L-arginine hydrochloride) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2].
| Name | Nω-Propyl-L-arginine hydrochloride |
|---|
| Description | Nω-Propyl-L-arginine hydrochloride (N-omega-Propyl-L-arginine hydrochloride) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. |
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| Related Catalog | |
| In Vivo | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) hydrochloride blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity[2]. Animal Model: Male NMRI mice (30-40 g) (phencyclidine-induced stimulation)[2] Dosage: 20 mg/kg Administration: I.p. Result: Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |
| References |
| Molecular Formula | C9H21ClN4O2 |
|---|---|
| Molecular Weight | 252.74 |