Nω-Propyl-L-arginine hydrochloride
Modify Date: 2024-06-19 17:10:46
Nω-Propyl-L-arginine hydrochloride structure
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Common Name | Nω-Propyl-L-arginine hydrochloride | ||
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| CAS Number | 2321366-46-3 | Molecular Weight | 252.74 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H21ClN4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Nω-Propyl-L-arginine hydrochlorideNω-Propyl-L-arginine hydrochloride (N-omega-Propyl-L-arginine hydrochloride) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. |
| Name | Nω-Propyl-L-arginine hydrochloride |
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| Description | Nω-Propyl-L-arginine hydrochloride (N-omega-Propyl-L-arginine hydrochloride) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. |
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| Related Catalog | |
| In Vivo | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) hydrochloride blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity[2]. Animal Model: Male NMRI mice (30-40 g) (phencyclidine-induced stimulation)[2] Dosage: 20 mg/kg Administration: I.p. Result: Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |
| References |
| Molecular Formula | C9H21ClN4O2 |
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| Molecular Weight | 252.74 |