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592517-80-1

592517-80-1 structure
592517-80-1 structure
  • Name: 11R-VIVIT
  • Chemical Name: 11R-VIVIT
  • CAS Number: 592517-80-1
  • Molecular Formula: C147H259N67O36S
  • Molecular Weight: 3573.15
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2020-08-11 18:09:50
  • Modify Date: 2024-01-11 15:18:29
  • 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.

Name 11R-VIVIT
Description 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.
Related Catalog
Molecular Formula C147H259N67O36S
Molecular Weight 3573.15