592517-80-1
592517-80-1 structure
- Name: 11R-VIVIT
- Chemical Name: 11R-VIVIT
- CAS Number: 592517-80-1
- Molecular Formula: C147H259N67O36S
- Molecular Weight: 3573.15
- Catalog: Signaling Pathways Others Others
- Create Date: 2020-08-11 18:09:50
- Modify Date: 2025-08-25 07:59:54
-
11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.
| Name | 11R-VIVIT |
|---|
| Description | 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. |
|---|---|
| Related Catalog |
| Molecular Formula | C147H259N67O36S |
|---|---|
| Molecular Weight | 3573.15 |