11R-VIVIT
Modify Date: 2025-08-25 07:59:54
11R-VIVIT structure
|
Common Name | 11R-VIVIT | ||
|---|---|---|---|---|
| CAS Number | 592517-80-1 | Molecular Weight | 3573.15 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C147H259N67O36S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 11R-VIVIT11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. |
| Name | 11R-VIVIT |
|---|
| Description | 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. |
|---|---|
| Related Catalog |
| Molecular Formula | C147H259N67O36S |
|---|---|
| Molecular Weight | 3573.15 |
| InChIKey | VNTCWMOQGXMIQP-PIQGMSCVSA-N |
| SMILES | CCC(C)C(NC(=O)C(NC(=O)C1CCCN1C(=O)C(Cc1cnc[nH]1)NC(=O)C1CCCN1C(=O)CNC(=O)C(C)NC(=O)C(CCSC)NC(=O)CNC(=O)CNC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(N)CCCNC(=N)N)C(C)C)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1CCCC1C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O)C(C)O)C(C)CC)C(C)C |