2244602-23-9

2244602-23-9 structure

Name: DBCO-PEG4-Val-Cit-PAB-MMAF
Chemical Name: DBCO-PEG4-Val-Cit-PAB-MMAF
CAS Number: 2244602-23-9
Molecular Formula: C₈₈H₁₂₆N₁₂O₂₀
Molecular Weight: 1672.01
Create Date: 2020-08-11 12:48:19
Modify Date: 2024-04-06 08:49:20
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	DBCO-PEG4-Val-Cit-PAB-MMAF

Description	DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer
Target	Auristatin
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula	C₈₈H₁₂₆N₁₂O₂₀
Molecular Weight	1672.01