1801838-28-7

1801838-28-7 structure
1801838-28-7 structure
  • Name: Mc-VC-PAB-SN38
  • Chemical Name: Mc-VC-PAB-SN38
  • CAS Number: 1801838-28-7
  • Molecular Formula: C51H58N8O13
  • Molecular Weight: 991.05
  • Create Date: 2020-08-11 16:39:43
  • Modify Date: 2024-01-02 21:25:02
  • Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name Mc-VC-PAB-SN38
Description Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Camptothecins

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula C51H58N8O13
Molecular Weight 991.05