442665-87-4
442665-87-4 structure
- Name: ST 045849
- Chemical Name: OGT-IN-2
- CAS Number: 442665-87-4
- Molecular Formula: C23H27ClN2O3S
- Molecular Weight: 446.99
- Catalog: Signaling Pathways Others Others
- Create Date: 2020-08-11 15:27:00
- Modify Date: 2025-08-25 17:30:11
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OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.
| Name | OGT-IN-2 |
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| Description | OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice. |
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| Related Catalog |
| Molecular Formula | C23H27ClN2O3S |
|---|---|
| Molecular Weight | 446.99 |
| Hazard Codes | Xi |
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