916888-47-6
916888-47-6 structure
- Name: Resolvin D3
- Chemical Name: Resolvin D3
- CAS Number: 916888-47-6
- Molecular Formula: C22H32O5
- Molecular Weight: 376.49
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2020-08-10 23:11:31
- Modify Date: 2024-01-14 17:05:02
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Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].
| Name | Resolvin D3 |
|---|
| Description | Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells[2]. |
| In Vivo | Resolvin D3 (RvD3; 100 ng/100 µl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis[1]. Animal Model: Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1] Dosage: 100 ng/100 µl Administration: IP; daily for 6 days Result: Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis. |
| References |
| Molecular Formula | C22H32O5 |
|---|---|
| Molecular Weight | 376.49 |