Resolvin D3
Modify Date: 2024-01-14 17:05:02
Resolvin D3 structure
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Common Name | Resolvin D3 | ||
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| CAS Number | 916888-47-6 | Molecular Weight | 376.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H32O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Resolvin D3Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2]. |
| Name | Resolvin D3 |
|---|
| Description | Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2]. |
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| Related Catalog | |
| In Vitro | RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells[2]. |
| In Vivo | Resolvin D3 (RvD3; 100 ng/100 µl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis[1]. Animal Model: Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1] Dosage: 100 ng/100 µl Administration: IP; daily for 6 days Result: Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis. |
| References |
| Molecular Formula | C22H32O5 |
|---|---|
| Molecular Weight | 376.49 |