Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VH 032, phenol
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2244684-42-0

2244684-42-0 structure

2244684-42-0 structure

Name: VH 032, phenol
Chemical Name: VH032-OH
CAS Number: 2244684-42-0
Molecular Formula: C₂₄H₃₂N₄O₅S
Molecular Weight: 488.60
Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
Create Date: 2020-08-08 09:20:59
Modify Date: 2024-01-14 09:03:07
VH032-OH is the VH032-based VHL ligand. VH032-OH can be connected to the ligand for protein by a linker to form PROTACs[1].

Name	VH032-OH

Description	VH032-OH is the VH032-based VHL ligand. VH032-OH can be connected to the ligand for protein by a linker to form PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017;8(1):830. Published 2017 Oct 10.

Molecular Formula	C₂₄H₃₂N₄O₅S
Molecular Weight	488.60

Hazard Codes	Xi

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.