1802086-25-4

1802086-25-4 structure

Name: GIP (3-42), human
Chemical Name: Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt
CAS Number: 1802086-25-4
Molecular Formula: C₂₁₆H₃₂₅F₃N₅₈O₆₅S
Molecular Weight: 4749.9
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Insulin Receptor
Create Date: 2020-11-24 20:28:44
Modify Date: 2024-01-10 08:14:06
GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo[1].

Name	Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt
Synonyms	MFCD18782440

Description	GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor
In Vitro	The incretin hormone GIP is rapidly degraded in the circulation by dipeptidyl peptidase IV (DPP IV) forming the N-terminally truncated peptide GIP(3-42)[1].
References	[1]. V A Gault, et al. Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo. J Endocrinol. 2002 Nov;175(2):525-33.