1926163-38-3

1926163-38-3 structure

Name: (D-Ser(tBu)6,D-Leu7,AzaGly10)-LHRH
Chemical Name: (D-Ser(tBu)6,D-Leu7,AzaGly10)-LHRH
CAS Number: 1926163-38-3
Molecular Formula: C₅₉H₈₄N₁₈O₁₄
Molecular Weight: 1269.411
Catalog: Signaling Pathways GPCR/G Protein GNRH Receptor
Create Date: 2021-01-12 19:35:03
Modify Date: 2024-05-02 10:40:13
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].

Name	(D-Ser(tBu)6,D-Leu7,AzaGly10)-LHRH
Synonyms	MFCD05663457 (2S)-N-[(2S,5S,8S,11S,14R,17R,20S)-25-Amino-20-({(2S)-2-[(2-carbamoylhydrazino)carbonyl]-1-pyrrolidinyl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-4-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-isobutyl-14-{[(2-methyl-2-propanyl)oxy]methyl}-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxo-2-pyrrolidinecarboxamide

Description	(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Endocrinology
References	[1]. Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53.