- DC Chemicals Limited
- China
- Product Name: ICI118630
- Price: $450.0/100mg $800.0/250mg $1600.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: (D-Ser(tBu)6,Azagly10)-LHRH
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Goserelin acetate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
145781-92-6
145781-92-6 structure
- Name: (D-Ser(tBu)6,AzaGly10)-LHRH acetate salt
- Chemical Name: Goserelin Acetate
- CAS Number: 145781-92-6
- Molecular Formula: C61H88N18O16
- Molecular Weight: 1329.46
- Catalog: API Hormone and endocrine-regulating drugs Gonadotropin
- Create Date: 2018-02-07 08:00:00
- Modify Date: 2024-01-02 02:35:58
-
Goserelin (ICI 118630) acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist).IC50 value:Target: GnRH agonistGoserelin is used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transsexuals and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot. Goserelin stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner.
| Name | Goserelin Acetate |
|---|---|
| Synonyms |
Goserelin acetate
Goserelin acetate [D-Ser(tBu)6,Azagly10]-LHRH acetate salt Goserelin (acetate) |
| Description | Goserelin (ICI 118630) acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist).IC50 value:Target: GnRH agonistGoserelin is used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transsexuals and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot. Goserelin stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. |
|---|---|
| Related Catalog |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 1695.5ºC at 760mmHg |
| Melting Point | >190°C (dec.) |
| Molecular Formula | C61H88N18O16 |
| Molecular Weight | 1329.46 |
| PSA | 493.39000 |
| LogP | -0.95 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.692 |
| Storage condition | −20°C |
| Water Solubility | H2O: 20 mg/mL, clear, colorless |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360 |
| Precautionary Statements | P201-P280-P308 + P313 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | OK6369800 |