Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SHIP 2a
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Cystathionine-γ-lyase-IN-1
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2165706-30-7

2165706-30-7 structure

2165706-30-7 structure

Name: SHIP 2a
Chemical Name: Cystathionine-γ-lyase-IN-1
CAS Number: 2165706-30-7
Molecular Formula: C₇H₈N₂O₂S
Molecular Weight: 184.22
Catalog: Research Areas Inflammation/Immunology
Create Date: 2021-01-06 10:38:23
Modify Date: 2025-08-26 00:35:27
Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1].

Name	Cystathionine-γ-lyase-IN-1

Description	Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
In Vitro	Cystathionine-γ-lyase-IN-1 (comp 2a) completely abrogates L-cysteine-induced vasorelaxation at a concentration of 100 μM[1]. Cystathionine-γ-lyase-IN-1 (100 μM; 30 minutes) significantly inhibits the increased H2S production stimulated by L-Cys at a lower dose in mouse aorta homogenates[1]. Cystathionine-γ-lyase-IN-1 inhibits the enzyme completely, keeping the concentration of substrate unaffected[1].
References	[1]. Angela Corvino, et al. Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci Rep. 2016 Oct 6;6:34398.

Molecular Formula	C₇H₈N₂O₂S
Molecular Weight	184.22

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