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2165706-30-7

2165706-30-7 structure
2165706-30-7 structure
  • Name: SHIP 2a
  • Chemical Name: Cystathionine-γ-lyase-IN-1
  • CAS Number: 2165706-30-7
  • Molecular Formula: C7H8N2O2S
  • Molecular Weight: 184.22
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2021-01-06 10:38:23
  • Modify Date: 2024-01-13 21:47:14
  • Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1].

Name Cystathionine-γ-lyase-IN-1
Description Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM[1].
Related Catalog
In Vitro Cystathionine-γ-lyase-IN-1 (comp 2a) completely abrogates L-cysteine-induced vasorelaxation at a concentration of 100 μM[1]. Cystathionine-γ-lyase-IN-1 (100 μM; 30 minutes) significantly inhibits the increased H2S production stimulated by L-Cys at a lower dose in mouse aorta homogenates[1]. Cystathionine-γ-lyase-IN-1 inhibits the enzyme completely, keeping the concentration of substrate unaffected[1].
References

[1]. Angela Corvino, et al. Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production. Sci Rep. 2016 Oct 6;6:34398.

Molecular Formula C7H8N2O2S
Molecular Weight 184.22