1164464-14-5

1164464-14-5 structure

Name: TG6-129
Chemical Name: TG6-129
CAS Number: 1164464-14-5
Molecular Formula: C₂₀H₁₈FN₅O₃S₃
Molecular Weight: 491.582
Create Date: 2021-01-08 12:08:27
Modify Date: 2024-01-07 13:45:17
TG6-129 is a selective antagonist of the EP2 receptor. TG6-129 reduces the expression of inflammatory factors induced by butaprost in P388D1 macrophages[1].

Name	TG6-129
Synonyms	2-Propenamide, N-[[[4-[[(5-ethyl-1,3,4-thiadiazol-2-yl)amino]sulfonyl]phenyl]amino]thioxomethyl]-3-(4-fluorophenyl)-, (2E)- (2E)-N-({4-[(5-Ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}carbamothioyl)-3-(4-fluorophenyl)acrylamide TG6-129

Description	TG6-129 is a selective antagonist of the EP2 receptor. TG6-129 reduces the expression of inflammatory factors induced by butaprost in P388D1 macrophages[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
References	[1]. Ganesh T, et al. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. ACS Med Chem Lett. 2013 Jul 11;4(7):616-621.