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157047-96-6

157047-96-6 structure
157047-96-6 structure
  • Name: Benzomalvin-A
  • Chemical Name: Benzomalvin A
  • CAS Number: 157047-96-6
  • Molecular Formula: C24H19N3O2
  • Molecular Weight: 381.427
  • Create Date: 2021-01-11 14:02:02
  • Modify Date: 2025-08-26 19:56:28
  • Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].

Name Benzomalvin A
Synonyms 7-Benzyl-6-methyl-6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
Benzomalvin A
Quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione, 6,7-dihydro-6-methyl-7-(phenylmethyl)-
Description Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].
Related Catalog
References

[1]. Sun HH, et al. Benzomalvins, new substance P inhibitors from a Penicillium sp. J Antibiot (Tokyo). 1994;47(5):515-522.

Density 1.3±0.1 g/cm3
Boiling Point 599.3±60.0 °C at 760 mmHg
Molecular Formula C24H19N3O2
Molecular Weight 381.427
Flash Point 316.3±32.9 °C
Exact Mass 381.147736
LogP 2.19
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.688
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