Benzomalvin-A

Modify Date: 2024-01-13 14:30:44

Benzomalvin-A Structure
Benzomalvin-A structure
Common Name Benzomalvin-A
CAS Number 157047-96-6 Molecular Weight 381.427
Density 1.3±0.1 g/cm3 Boiling Point 599.3±60.0 °C at 760 mmHg
Molecular Formula C24H19N3O2 Melting Point N/A
MSDS N/A Flash Point 316.3±32.9 °C

 Use of Benzomalvin-A


Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].

 Names

Name Benzomalvin A
Synonym More Synonyms

 Benzomalvin-A Biological Activity

Description Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].
Related Catalog
References

[1]. Sun HH, et al. Benzomalvins, new substance P inhibitors from a Penicillium sp. J Antibiot (Tokyo). 1994;47(5):515-522.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 599.3±60.0 °C at 760 mmHg
Molecular Formula C24H19N3O2
Molecular Weight 381.427
Flash Point 316.3±32.9 °C
Exact Mass 381.147736
LogP 2.19
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.688

 Synonyms

7-Benzyl-6-methyl-6,7-dihydroquinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
Benzomalvin A
Quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione, 6,7-dihydro-6-methyl-7-(phenylmethyl)-