1919050-87-5
1919050-87-5 structure
- Name: RL648_81
- Chemical Name: RL648_81
- CAS Number: 1919050-87-5
- Molecular Formula: C17H17F4N3O2
- Molecular Weight: 371.33
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2021-01-13 12:23:30
- Modify Date: 2024-09-02 07:40:31
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RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has the potential for neurologic disorders associated with neuronal hyperexcitability research[1].
| Name | RL648_81 |
|---|---|
| Synonyms |
Carbamic acid, N-[2-amino-3-fluoro-4-[[[4-(trifluoromethyl)phenyl]methyl]amino]phenyl]-, ethyl ester
Ethyl (2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate Ethyl (2-amino-3-fluoro-4-{[4-(trifluoromethyl)benzyl]amino}phenyl)carbamate RL648_81 |
| Description | RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has the potential for neurologic disorders associated with neuronal hyperexcitability research[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 412.8±45.0 °C at 760 mmHg |
| Molecular Formula | C17H17F4N3O2 |
| Molecular Weight | 371.33 |
| Flash Point | 203.4±28.7 °C |
| Exact Mass | 371.125702 |
| LogP | 1.97 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.595 |