2032282-97-4

2032282-97-4 structure

Name: Rbin-2
Chemical Name: Rbin-2
CAS Number: 2032282-97-4
Molecular Formula: C₁₃H₁₁BrN₄S
Molecular Weight: 335.22
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2021-01-11 23:39:51
Modify Date: 2024-01-13 16:36:53
Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].

Name	Rbin-2
Synonyms	7-Bromo-2-(2-methyl-allylsulfanyl)-9H-1,3,4,9-tetraaza-fluorene 5H-1,2,4-Triazino[5,6-b]indole, 7-bromo-3-[(2-methyl-2-propen-1-yl)thio]- Rbin-2 7-Bromo-3-[(2-methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole 7-Bromo-3-[(2-methyl-2-propen-1-yl)thio]-5H-1,2,4-Triazino[5,6-b]indole

Description	Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Others
References	[1]. Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167(2):512-524.e14.