Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BPU-11
Price: Check
Purity: 98.37%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: BPU-11
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: BPU-11
Price: ￥650.0/100mg ￥1200.0/250mg ￥2400.0/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

909664-41-1

909664-41-1 structure

909664-41-1 structure

Name: BPU-11
Chemical Name: BPU-11
CAS Number: 909664-41-1
Molecular Formula: C₃₂H₃₁N₅O
Molecular Weight: 501.62144
Catalog: Signaling Pathways Membrane Transporter/Ion Channel HCN Channel
Create Date: 2021-05-21 17:50:00
Modify Date: 2024-09-17 20:26:15
BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease[1].

Name	BPU-11

Description	BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> HCN Channel
In Vitro	BPU-11 (100 μM) 消除了 HCN4 cAMP 诱导的 V1/2 位移，k1/2 为 0.42 μM[1]。 BPU (100 和 200 μM) 是 HCN4 亚型特异性的，对 HEK293T 细胞中表达的 HCN2 通道无影响[1]。
References	[1]. Lolicato M, et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat Chem Biol. 2014 Jun;10(6):457-62.

Molecular Formula	C₃₂H₃₁N₅O
Molecular Weight	501.62144

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