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  • DC Chemicals Limited
  • China
  • Product Name: 5-LOX-IN-2
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Tony Cao

179691-97-5

179691-97-5 structure
179691-97-5 structure
  • Name: 2,5-Dihydroxycinnamic Acid phenethyl ester
  • Chemical Name: 2,5-Dihydroxycinnamic Acid phenethyl ester
  • CAS Number: 179691-97-5
  • Molecular Formula: C17H16O4
  • Molecular Weight: 284.31
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
  • Create Date: 2021-04-30 13:15:39
  • Modify Date: 2024-01-20 13:25:00
  • 5-LOX-IN-2, an inhibitor of 5-lipoxygenase (5-LOX) with an IC50 of 0.33 μM, inhibits 5-LOX in a dose-dependent manner . 5-LOX-IN-2, reduces the cell viability of renal cancer cells and induces apoptosis, can be used for cancer research[1].

Name 2,5-Dihydroxycinnamic Acid phenethyl ester
Synonyms 2-Phenylethyl (2E)-3-(2,5-dihydroxyphenyl)acrylate
2-phenylethyl (2E)-3-(2,5-dihydroxyphenyl)prop-2-enoate
β-Phenylethyl 2,5-dihydroxycinnamate
2-Propenoic acid, 3-(2,5-dihydroxyphenyl)-, 2-phenylethyl ester, (2E)-
Description 5-LOX-IN-2, an inhibitor of 5-lipoxygenase (5-LOX) with an IC50 of 0.33 μM, inhibits 5-LOX in a dose-dependent manner . 5-LOX-IN-2, reduces the cell viability of renal cancer cells and induces apoptosis, can be used for cancer research[1].
Related Catalog
Target

5-LOX:0.33 μM (IC50)

References

[1]. Selka A, et.al. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Eur J Med Chem. 2019 Oct 1;179:347-357.  

Density 1.3±0.1 g/cm3
Boiling Point 515.5±50.0 °C at 760 mmHg
Molecular Formula C17H16O4
Molecular Weight 284.31
Flash Point 192.2±23.6 °C
Exact Mass 284.104858
LogP 3.70
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.646