917382-84-4

917382-84-4 structure

Name: Homodestcardin
Chemical Name: Homodestcardin
CAS Number: 917382-84-4
Molecular Formula: C₃₂H₅₅N₅O₇
Molecular Weight: 621.808
Catalog: Research Areas Inflammation/Immunology
Create Date: 2021-04-27 15:35:41
Modify Date: 2025-11-03 20:15:44
Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM[1].

Name	Homodestcardin
Synonyms	(3S,6S,9S,16R,21S,21aS)-3,6-Di[(2S)-2-butanyl]-16-isobutyl-5,8,9,21-tetramethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone homodestcardin Pyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone, dodecahydro-5,8,9,21-tetramethyl-3,6-bis[(1S)-1-methylpropyl]-16-(2-methylpropyl)-, (3S,6S,9S,16R,21S,21aS)-

Description	Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Ai Hua Zhang, et al. Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motif. Chem Asian J. 2013 Dec;8(12):3101-7.