Homodestcardin

Modify Date: 2025-11-03 20:15:44

Homodestcardin Structure
Homodestcardin structure
Common Name Homodestcardin
CAS Number 917382-84-4 Molecular Weight 621.808
Density 1.2±0.1 g/cm3 Boiling Point 879.1±65.0 °C at 760 mmHg
Molecular Formula C32H55N5O7 Melting Point N/A
MSDS N/A Flash Point 485.5±34.3 °C

 Use of Homodestcardin


Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM[1].

 Names

Name Homodestcardin
Synonym More Synonyms

 Homodestcardin Biological Activity

Description Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM[1].
Related Catalog
References

[1]. Ai Hua Zhang, et al. Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motif. Chem Asian J. 2013 Dec;8(12):3101-7.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 879.1±65.0 °C at 760 mmHg
Molecular Formula C32H55N5O7
Molecular Weight 621.808
Flash Point 485.5±34.3 °C
Exact Mass 621.410156
LogP 0.17
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.532
InChIKey AIPPDKJKKDOWTJ-MKUQIKACSA-N
SMILES CCC(C)C1NC(=O)C2C(C)CCN2C(=O)C(CC(C)C)OC(=O)CCNC(=O)C(C)N(C)C(=O)C(C(C)CC)N(C)C1=O

 Synonyms

(3S,6S,9S,16R,21S,21aS)-3,6-Di[(2S)-2-butanyl]-16-isobutyl-5,8,9,21-tetramethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone
homodestcardin
Pyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone, dodecahydro-5,8,9,21-tetramethyl-3,6-bis[(1S)-1-methylpropyl]-16-(2-methylpropyl)-, (3S,6S,9S,16R,21S,21aS)-
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