937738-63-1

937738-63-1 structure

Name: Resolvin D1 methyl ester
Chemical Name: Resolvin D1 methyl ester
CAS Number: 937738-63-1
Molecular Formula: C₂₃H₃₄O₅
Molecular Weight: 390.513
Catalog: Research Areas Metabolic Disease
Create Date: 2021-04-29 11:52:39
Modify Date: 2024-01-12 07:15:10
Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1 (HY-125527). Resolvin D1 methyl ester reduces triglyceride levels[1].

Name	Resolvin D1 methyl ester
Synonyms	Resolvin D1 methyl ester Methyl (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxy-4,9,11,13,15,19-docosahexaenoate RvD1-ME 4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, methyl ester, (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-

Description	Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1 (HY-125527). Resolvin D1 methyl ester reduces triglyceride levels[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	Treating diabetic mice with menhaden oil in the diet or exogenously with resolvins D1 and E1 or the methyl esters of resolvins D1 (1 ng/g ; i.p.; daily) and D2 reduced triglyceride levels to control values or lower in type 2 diabetes C57BL/6J mice[1]. Treating diabetic mice with the methyl esters of resolvins D1 or D2 significantly improved motor nerve conduction velocity compared to non-treated diabetic mice but both motor and sensory nerve conduction velocities in these treated mice remained significantly impaired compared to control mice[1].
References	[1]. Alexander Obrosov, et al. Effect of Fish Oil vs. Resolvin D1, E1, Methyl Esters of Resolvins D1 or D2 on Diabetic Peripheral Neuropathy. J Neurol Neurophysiol. 2017;8(6):453.