61468-88-0

61468-88-0 structure
61468-88-0 structure
  • Name: 2'-NH2-ATP
  • Chemical Name: 2'-NH2-ATP
  • CAS Number: 61468-88-0
  • Molecular Formula: C10H17N6O12P3
  • Molecular Weight: 506.20
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2021-09-13 16:23:18
  • Modify Date: 2024-01-10 19:18:31
  • 2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling[1][2][3].

Name 2'-NH2-ATP
Description 2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling[1][2][3].
Related Catalog
In Vitro 2'-NH2-ATP (2 mM) did not replace ATP as a substrate for NH3-dependent cytidine 5'-triphosphate (CTP) formation catalyzed by CTP synthase[2].
References

[1]. Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8.

[2]. Faylene A. L. KINETIC STUDIES ON WILD-TYPE AND MUTANT ESCHERICHIA COLICYTIDINE 5'-TRIPHOSPHATE SYNTHASES AND INHIBITOR DEVELOPMENT. Dalhousie University Halifax, Nova Scotia. 2008 Jul.

[3]. Aström H, et, al. Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides. J Am Chem Soc. 2004 Nov 17;126(45):14710-1.

Molecular Formula C10H17N6O12P3
Molecular Weight 506.20
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