190581-71-6

190581-71-6 structure

Name: (R)-Lanicemine
Chemical Name: (R)-Lanicemine
CAS Number: 190581-71-6
Molecular Formula: C₁₃H₁₄N₂
Molecular Weight: 198.26
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2021-09-10 11:47:35
Modify Date: 2024-01-06 16:04:22
(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].

Name	(R)-Lanicemine

Description	(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.

Molecular Formula	C₁₃H₁₄N₂
Molecular Weight	198.26