(R)-Lanicemine

Modify Date: 2024-01-06 16:04:22

(R)-Lanicemine Structure
(R)-Lanicemine structure
Common Name (R)-Lanicemine
CAS Number 190581-71-6 Molecular Weight 198.26
Density N/A Boiling Point N/A
Molecular Formula C13H14N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-Lanicemine


(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].

 Names

Name (R)-Lanicemine

 (R)-Lanicemine Biological Activity

Description (R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].
Related Catalog
References

[1]. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.

 Chemical & Physical Properties

Molecular Formula C13H14N2
Molecular Weight 198.26