1855860-24-0
1855860-24-0 structure
- Name: DS-1205b free base
- Chemical Name: DS-1205b free base
- CAS Number: 1855860-24-0
- Molecular Formula: C41H42FN5O7
- Molecular Weight: 735.80
- Create Date: 2021-07-04 10:35:35
- Modify Date: 2025-08-25 12:30:44
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DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.
| Name | DS-1205b free base |
|---|
| Description | DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo. |
|---|
| Molecular Formula | C41H42FN5O7 |
|---|---|
| Molecular Weight | 735.80 |