20950-52-1

20950-52-1 structure

Name: 3,7-DMF
Chemical Name: 3,7-dimethoxy-2-(3',4'-methylenedioxy-phenyl)chromen-4-one
CAS Number: 20950-52-1
Molecular Formula: C₁₇H₁₄O₄
Molecular Weight: 282.29
Catalog: Signaling Pathways Stem Cell/Wnt TGF-beta/Smad
Create Date: 2017-11-20 14:36:54
Modify Date: 2024-01-02 19:00:13
3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].

Name	3,7-dimethoxy-2-(3',4'-methylenedioxy-phenyl)chromen-4-one
Synonyms	3.7-Dimethoxy-flavon 3,7-Dimethoxyflavone 3,7-dimethoxy-2-phenyl-chromen-4-one 3,7-Dimethoxy-2-phenyl-chromen-4-on

Description	3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad Research Areas >> Others
References	[1]. Hyomin Park , et al. Discovery of 3,7-dimethoxyflavone that inhibits liver fibrosis based on dual mechanisms of antioxidant and inhibitor of activated hepatic stellate cell. Free Radic Biol Med.2023, 204.

HS Code	2914509090

Precursor 0
DownStream 2
7478-60-6 492-00-2

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%