3,7-DMF

Modify Date: 2025-08-25 11:25:18

3,7-DMF structure	Common Name	3,7-DMF
	CAS Number	20950-52-1	Molecular Weight	282.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3,7-DMF

3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].

Name	3,7-dimethoxy-2-(3',4'-methylenedioxy-phenyl)chromen-4-one
Synonym	More Synonyms

Description	3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad Research Areas >> Others
References	[1]. Hyomin Park , et al. Discovery of 3,7-dimethoxyflavone that inhibits liver fibrosis based on dual mechanisms of antioxidant and inhibitor of activated hepatic stellate cell. Free Radic Biol Med.2023, 204.

Molecular Formula	C₁₇H₁₄O₄
Molecular Weight	282.29
Exact Mass	282.08900
PSA	48.67000
LogP	3.47720
InChIKey	CNDZOPXQZSXGSK-UHFFFAOYSA-N
SMILES	COc1ccc2c(=O)c(OC)c(-c3ccccc3)oc2c1

HS Code	2914509090

Precursor 0
DownStream 2
CAS#:7478-60-6 4H-1-Benzopyran... CAS#:492-00-2 3,7-dihydroxyflavone

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100

Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101

Name: Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B3
External Id: CHEMBL3039491

Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015

Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary ...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2Venus

Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE

Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE

Name: Confirmatory qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 ...
Source: NCGC
External Id: epac1-activator-f1f2f3f4

Name: Confirmatory qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor...
Source: NCGC
External Id: epac1-inhibitor-f1f2f3f4

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3.7-Dimethoxy-flavon

3,7-Dimethoxyflavone

3,7-dimethoxy-2-phenyl-chromen-4-one

3,7-Dimethoxy-2-phenyl-chromen-4-on

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3,7-DMF

Use of 3,7-DMF

Names

3,7-DMF Biological Activity

Chemical & Physical Properties

Safety Information

Precursor & DownStream

Customs

3,7-DMFBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.