650621-20-8

650621-20-8 structure

Name: PTP1B-IN-13
Chemical Name: N-({4-[(3,4-Dimethylphenyl)sulfamoyl]phenyl}carbamothioyl)-3-phenylpropanamide
CAS Number: 650621-20-8
Molecular Formula: C₂₄H₂₅N₃O₃S₂
Molecular Weight: 467.60
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2021-09-16 16:48:02
Modify Date: 2024-01-14 23:09:50
PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.

Name	N-({4-[(3,4-Dimethylphenyl)sulfamoyl]phenyl}carbamothioyl)-3-phenylpropanamide
Synonyms	Benzenepropanamide, N-[[[4-[[(3,4-dimethylphenyl)amino]sulfonyl]phenyl]amino]thioxomethyl]- MFCD04104932 N-({4-[(3,4-Dimethylphenyl)sulfamoyl]phenyl}carbamothioyl)-3-phenylpropanamide PTP1B-IN-13

Description	PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Others
References	[1]. Yang Y, et al. Integrated Approach to Identify Selective PTP1B Inhibitors Targeting the Allosteric Site. J Chem Inf Model. 2021 Sep 27;61(9):4720-4732.