Shanghai Nianxing Industrial Co., Ltd
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Product Name: beta-Eudesmol
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: beta-eudesmol
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473-15-4

473-15-4 structure

473-15-4 structure

Name: beta-Eudesmol
Chemical Name: β-eudesmol
CAS Number: 473-15-4
Molecular Formula: C₁₅H₂₆O
Molecular Weight: 222.366
Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
Create Date: 2018-02-27 08:00:00
Modify Date: 2025-08-20 10:00:05
Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1[1].

Name	β-eudesmol
Synonyms	2-[(2R,4aR,8aS)-4a-Methyl-8-methylenedecahydronaphthalen-2-yl]propan-2-ol 2-[(2R,4aR,8aS)-4a-methyl-8-methylidenedecahydronaphthalen-2-yl]propan-2-ol Eudesm-4(14)-en-11-ol 2-[(2R,4aR,8aS)-4a-methyl-8-methylidene-1,2,3,4,5,6,7,8a-octahydronaphthalen-2-yl]propan-2-ol b-Eudesmol 2-[(2R,4aR,8aS)-4a-Methyl-8-methylenedecahydro-2-naphthalenyl]-2-propanol Eudesmol. B. 2-Naphthalenemethanol, decahydro-α,α,4a-trimethyl-8-methylene-, (2R,4aR,8aS)- beta-eudesmol (+)-b-Eudesmol rel-2-[(2R,4aR,8aS)-4a-methyl-8-methylenedecahydronaphthalen-2-yl]propan-2-ol \|A-Eudesmol Eudesm-4(14)-en-11-ol (8CI) 1,2a,3,4,4a,5,6,7,8,8aa-Decahydro-a,a,4ab-trimethyl-8-methylene-2-naphthalenemethanol b-Selinenol

Description	Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Metabolic Disease
References	[1]. Ohara K, et al. β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system. Sci Rep. 2017 Nov 17;7(1):15785. [2]. Ohara K, et al. Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oil. J Biol Chem. 2015 Jan 30;290(5):3161-71.

Density	1.0±0.1 g/cm3
Boiling Point	301.7±11.0 °C at 760 mmHg
Melting Point	72-74ºC
Molecular Formula	C₁₅H₂₆O
Molecular Weight	222.366
Flash Point	108.6±15.6 °C
Exact Mass	222.198364
PSA	20.23000
LogP	4.68
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.499
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ9698500

CHEMICAL NAME :: 2-Naphthalenemethanol, decahydro-8-methylene-alpha,alpha,4a-trimethyl-, (2R-(2-alpha,4a- alpha,8a-beta)-

CAS REGISTRY NUMBER :: 473-15-4

LAST UPDATED :: 199703

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H26-O

MOLECULAR WEIGHT :: 222.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-13629

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	QJ9698500

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