Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-Maleimidovaleric acid
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-Maleimidovaleric acid
Price: ￥498.0/25mg ￥1198.0/100mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-MALEIMIDOVALERIC ACID(DMVA)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

57078-99-6

57078-99-6 structure

57078-99-6 structure

Name: 5-Maleimidovaleric acid
Chemical Name: 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
CAS Number: 57078-99-6
Molecular Formula: C₉H₁₁NO₄
Molecular Weight: 197.188
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-04-27 08:00:00
Modify Date: 2024-01-12 15:48:38
5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
Synonyms	5-(2,5-dioxopyrrol-1-yl)pentanoic acid 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid 1H-Pyrrole-1-pentanoic acid, 2,5-dihydro-2,5-dioxo- 5-Maleimidovaleric acid

Description	5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density	1.3±0.1 g/cm3
Boiling Point	400.7±28.0 °C at 760 mmHg
Molecular Formula	C₉H₁₁NO₄
Molecular Weight	197.188
Flash Point	196.2±24.0 °C
Exact Mass	197.068802
PSA	74.68000
LogP	0.56
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.544

Hazard Codes	Xi
HS Code	2925190090

108-31-6 structure

108-31-6

660-88-8 structure

660-88-8

~60%

57078-99-6 structure

57078-99-6

Literature: De Figueiredo, Renata Marcia; Oczipka, Philipp; Froehlich, Roland; Christmann, Mathias Synthesis, 2008 , # 8 p. 1316 - 1318

Precursor 2
108-31-6 660-88-8
DownStream 0

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%